The efficacy and function of Fritillaria thunbergii

I wonder if you have ever heard of Fritillaria thunbergii. Fritillaria thunbergii has great benefits for regulating our body and can also play a good role in treating some diseases. Today let us look at the relevant knowledge about Fritillaria thunbergii.

[Other names] Fritillaria thunbergii (Selected Chinese Herbal Medicines in Yunnan), Tripterygium wilfordii (Tianjin Medical Newsletter (10): 16-22, 1971)

[Source] It is the bulb of the Liliaceae plant , Sagittaria sagittifolia . Harvested in summer and autumn.

[Original form] Perennial herb, about 20 cm high. The bulb is spherical, about 1 cm in diameter, and has a brown outer skin. The stem is single, the part below the soil is white, and the part above the soil is purple. The leaves are linear, about 15 cm long and 0.5 cm wide, gradually pointed at the apex, sheath-like at the base, and have parallel longitudinal veins. The flowers are purple, 1.5 to 2 cm in diameter, and the inflorescence is racemose, with 2 to 3 flowers. Perianth lobes 6, separate; stamens 6, anthers introrse. Capsule oblong, about 7 mm wide. Flowering period is summer.

[Habitat distribution] Grown on hillside grasslands or under pine forests. Distributed in Yunnan, Tibet and other places.

[Chemical composition] The bulb, stem, leaf and seed contain colchicine, β-photocolchicine, horncolchicine, N-formyl-N-deacetylcolchicine and other biological alkaloids.

[Toxicity] Trillium contains a large amount of colchicine, which is oxidized into dicolchicine oxide in the body after oral administration. It is highly toxic and can cause severe irritation symptoms to the digestive and urinary systems. It has an inhibitory effect on the nervous system and produces ascending paralysis. If the diaphragm is affected, it can cause respiratory movement disorders. In severe cases, water and electrolyte imbalance may occur, causing hypochloremia, hypokalemia, alkali poisoning or acidosis, and varying degrees of shock symptoms, or even death from respiratory failure. The total amount of colchicine in the body within 24 hours should not exceed 6 mg, and its lethal dose is about 20 to 20 mg. Even if the patient escapes danger after emergency treatment, bone marrow hematopoietic dysfunction and a decrease in white blood cell count may still occur in the later stages. The principle of first aid is to treat the symptoms and prevent and treat various complications, including gastric lavage, catharsis, infusion, adjustment of electrolyte balance, anti-shock, oxygen administration, etc. In the later stage, cell growth-promoting drugs are mainly used, and recovery is expected. Because the symptoms of poisoning are similar to those of atropine, it is best not to use atropine.

[Properties and flavors] "Selected Yunnan Chinese Herbal Medicines": "bitter, warm, and poisonous."

【Functions and indications】Anti-asthma, antitussive, analgesic, and anti-cancer. Treat bronchitis, asthma, breast cancer, and nasopharyngeal cancer.

[Clinical Application] Treatment of breast cancer with Trillium and its bio-alkaline preparations: 1. Trillium powder: Grind the bulb part of Trillium powder into powder, 0.5 grams per packet, 1 packet each time, 4 times a day, a total of 40 to 50 grams for a course of treatment. 2. Zhengguang 81 injection: Each vial contains 1 mg of colchicine. Take 2 vials each time. Dilute with 500 ml of 5% glucose solution and then drip intravenously once a day. The total amount is 40-60 mg per course of treatment. ㈢Zhengguang 81-A tablet: Made from colchicine derivative, namely colchicine amide, each tablet contains 2.5 mg of colchicine amide, 2 tablets each time, 4 times a day, with a total amount of 400-500 mg. The therapeutic effect is the same as "Zhengguang 81", but the side effects are greatly reduced. ㈣Zhengguang 81-A injection: Each vial contains 10 mg of colchicine. Take 1 vial each time. The injection method is the same as Zhengguang 81 injection. The total amount is 250-800 mg. 61 cases were treated with the above four preparations, and 56 cases showed different degrees of reduction, with an effective rate of 86.1%; in 5 cases, the tumors disappeared, and in 17 cases, the tumors were reduced to more than half of their original volume. Among them, 47 cases were treated with Zhengguang 81 injection, with an effective rate of 93.6% and significant effect of 42.5%. Intravenous infusion is the best route of administration.

【Excerpt】 《*Dictionary》

Through the above description, we know what Fritillaria thunbergii is and what effects it has. The medicinal value of Fritillaria thunbergii is very high and it is beneficial to improve the immune system. It is a worthy choice for us.