What is progesterone

Progesterone is a natural substance secreted by the corpus luteum of the ovary that can stimulate estrogen in the body. It has a significant effect on the endometrium and has an ecological effect on maintaining pregnancy. It is a good medication for pregnant women in daily life. The main effect of the drug is very critical. The main effect of progesterone is that progesterone in the late menstrual cycle of women will cause congestion and thickening of the uterine mucosal glands and endometrium.

Progesterone safely stimulates breast development. The combined effect of progesterone and lutein can fully develop the breasts. Progesterone can close the entrance of the uterus and reduce some other diseases. Progesterone is also a natural progestin and a common ovarian secretion. We will briefly introduce it below.

Drug alias: progesterone, progestin, Utrogestan, Progestin. English name: Progesterone. Injection: 10 mg (1 ml); 20 mg (1 ml) per vial. Capsules: 100 mg per capsule. Compound progesterone injection: light yellow clear oily liquid, 1 ml per vial, containing 20 mg of progesterone and 20 mg of estradiol benzoate. It has the same uses as progesterone, but has better efficacy. Inject 1 ml intramuscularly daily for 2 to 4 days. Triple hormone injection: It is a light yellow clear oily liquid, 1 ml per vial, containing 12.5 mg of progesterone, 25 mg of testosterone propionate and 1.5 mg of estradiol benzoate. Its usage is similar to compound progesterone injection, and it is mainly used for irregular menstruation, but the amount of withdrawal bleeding is less. It is also used for menopausal syndrome and milk withdrawal. Take 1 ml intramuscularly once a day or every other day, for 3 to 5 times.

Pharmacological Action

Progesterone is a natural progestin secreted by the corpus luteum of the ovary. It has a significant morphological effect on the estrogen-stimulated endometrium in the body and is necessary for maintaining pregnancy. Its main pharmacological effects are:

① In the later stage of the menstrual cycle, it causes the glands in the uterine mucosa to grow, the uterus to become congested, and the endometrium to thicken, preparing for the implantation of the fertilized egg. After the fertilized egg is implanted, it produces the placenta, reduces the excitability of the pregnant uterus, inhibits its activity, and allows the fetus to grow safely.

② Working together with estrogen, it promotes full development of the breasts in preparation for milk production.

③ It closes the cervix, reduces and thickens the mucus, making it difficult for sperm to penetrate; in large doses, it has a negative feedback effect on the hypothalamus, inhibiting the secretion of pituitary gonadotropin and producing an ovulation-inhibiting effect.

The above is the effect of progesterone. Progesterone can help inhibit ovulation. It can also make the breasts fully develop and increase the excitability of the uterus. Progesterone has many functions in our daily life. If progesterone is insufficient, it can also lead to some other types of diseases. Therefore, we must have a correct understanding of progesterone.