The efficacy and function of Hagi

Most Chinese medicinal materials have good effects on the treatment of diseases, such as Achyranthes bidentata. Below we will give a basic introduction to the relevant information of Achyranthes bidentata.

【English Name】 Suffrutescent Securinega Twig

[Other names] Artemisia scoparia, hengzi, vermicelli, mouse teeth, horse broom teeth, child's fist, leaf beads, dog tongue strips, eight leaf beads, mountain broom strips, dog apricot strips, flower broom strips, mountain sweeping strips, old rice drink, false kumquat vine, big carp diarrhea, kumquat, flower sweeping strips, child's fist

[Source] Medicinal material source: the tender branches, leaves or roots of the Euphorbiaceae plant Euphorbia pulex.

[Original form] Leaf-bottomed beads, shrubs, 1-3m high. The stems are clustered and branched, with green, slender, ridged twigs and the upper part mostly drooping; the old branches are gray-brown, smooth and hairless. Simple leaves are alternate; with short petioles; leaf blades are elliptic or elliptic in shape of a restaurant, entire or with irregular wavy teeth or slightly serrated. 3-12 flowers are clustered on the leaf vents; flowers are small, light yellow, and without petals; unisexual, monoecious; sepals are 5, ovate; male flower disc has 5 glands, separate, 2-lobed, 5 sepals are alternate, and the reduced ovary is small, cylindrical, 1mm long, and 2-lobed; female flower disc is almost undivided, ovary has 3 chambers, and style has 3 petals. The flowering period is from May to July, and the fruiting period is from July to September.

【Habitat distribution】Ecological environment: grows on hillsides or roadsides.

[Cultivation] Due to its biological characteristics, it is suitable to be planted on sunny flat land or hillside. The requirements for sealing are not strict, but it is better to use fertile, loose and loose ones.

[Properties] Identification of properties: The young branches are cylindrical, slightly angular, about 30-40cm long, and the diameter of the thick end is about 2mm. The surface is dark green-yellow, sometimes slightly red, with fine longitudinal texture. The texture is brittle, the cross section is fibrous, the center is white, the leaves are mostly wrinkled and broken, and sometimes there are yellow flowers or gray-black fruits. It has a faint smell and tastes slightly spicy and bitter.

[Chemical composition] The plant contains securinine and suffruticosine, and the leaves contain dihydrosecurinine. It also contains securinol A, securinol B, securinol C, allosecurinine, securinol A, securinol B, securinol C picrate and allosecurinine. Leaves and young stems contain a leaf of scutellaria.

[Pharmacological action] 1. Central nervous system excitatory effect: It has obvious excitatory effect on the central nervous system, especially the spinal cord. In small doses, it increases the excitability of reflexes and shortens the latency period of reflexes. In large doses, it produces strychnine-like convulsions. Both monochalcone and dihydrochalcone can cause this type of convulsion. Hagibis can significantly increase muscle tension, but it has no direct excitatory effect on neuromuscular tissues, and has no inhibitory effect on cholesterase and monoamine oxidase, so it is the result of its action on the central nervous system. The effect on the cerebral cortex is to strengthen conditioned reflexes, shorten the latency period, and the electroencephalogram shows an increase in fast waves and a decrease in slow waves. Hagibis can also increase oxygen consumption in the brain, spinal cord, liver, kidneys, and skeletal muscles. Its stimulating effect on the spinal cord can be used to treat the sequelae of polio. It can also treat facial nerve paralysis, not only restoring the paralyzed nerves, but also significantly reducing the rate of complete nerve degeneration in early-stage patients. Aconite has a stimulating effect on the spinal cord similar to strychnine, but its toxicity is far less than that of strychnine. Frogs, mice, rats, rabbits and cats all developed tonic and paroxysmal convulsions after injection of aconite. The decoction of aconite also has a central nervous system stimulating effect, but to a weaker degree. Like galantamine, galantamine is a cholesterase inhibitor and is therefore used clinically to treat diseases such as polio and its sequelae. D-securinine (d-sec.) 100 mg/kg injected into the frog lymph sac caused paroxysmal convulsions within 10-20 minutes, while l-sec. (l-sec.) 600 mg/kg injected in the same manner produced convulsions 2-3 hours later; 2. Cardiovascular effects: The decoction of d-securinine leaves has an excitatory effect on the hearts of toads and cats, while a small dose of d-sec. has no such effect; the decoction of d-securinine leaves and d-sec. nitrate both caused respiratory excitement and a decrease in blood pressure in rabbits and dogs. Intravenous injection of chlorhexidine in other anesthetized animals can increase blood pressure, strengthen cardiac contractility, and stimulate breathing. However, it had no vasoconstrictive effect on isolated rabbit ear vascular perfusion.

[Toxicity] Toxicity: Poisoning by strychnine can cause spinal convulsions, but it is weaker than strychnine. The amount that causes convulsions in cats is about 10.5 times that of strychnine, and the amount that causes death is about 100 times that of strychnine. Therefore, the treatment range is wider than that of strychnine. The median lethal dose for mice by intravenous injection is 6.3 mg/kg, for intraperitoneal injection it is 25 mg/kg, and for rats by intraperitoneal injection it is 41 mg/kg. It is also said that the median lethal dose for mice injected intravenously is 3.5 mg/kg. Toxicity was enhanced when mice were pretreated with SKF525-A or their livers were damaged by carbon tetrachloride. The excitatory effect and toxicity (median lethal dose) of dihydro-isothiazine on the central nervous system of mice are twice as strong as those of isothiazine. Continuous administration of nitrate for a long time had no significant effect on the growth and development, liver and kidney function, and red blood cells of animals.

[Preparation] Take green young branches with leaves, tie them into small bundles and dry them in the shade for later use. Roots: Remove dirt, wash, slice and dry for later use.

【Nature and flavor】 Pungent; bitter; slightly warm; slightly toxic

【Meridian】 Liver; Kidney; Spleen

【Functions and indications】 Dispel wind and promote blood circulation; benefit the kidneys and strengthen the tendons. Mainly used for rheumatic low back pain; numbness of limbs; impotence; infantile malnutrition; facial nerve paralysis; sequelae of poliomyelitis

[Usage and Dosage] For oral use: decocted in water, 6-9g.

[Additional prescription] 1. To treat infantile malnutrition: 5-6 qian of Iris chinensis root, 5-6 qian of Rhamnaceae Gulliver tea, 5-6 qian of Rhamnaceae Rhamnaceae Saposhnikovia divaricata root, 5-6 qian of Wild Hammerwort root, 5-6 qian of Strychnos nux vomica root, 5-6 qian of Indigofera chinensis root or stem, 14 roasted black soybeans (half-cooked), and 5 red dates. Decoction in water, add brown sugar, and take once in the morning and evening on an empty stomach. (Zhejiang Tianmu Yam Plant Records) 2. To treat impotence: 5 to 6 qian of one leaf autumn root. Decoction in water. (Hunan Pharmacopoeia)

[Discussions by various scholars] 1. "Guangxi Medicinal Plant List" is used to treat leucorrhea in women.

【Excerpt】 Chinese Materia Medica

Now you know the function of Hagibiscus scabra. I didn’t know that the leaf wormwood was such a valuable thing before, which shows that our knowledge is not broad enough. So in the future life, learning more about it can be a good way to maintain health. In fact, if you want to maintain your health, there is knowledge everywhere in life.