Niuhuang Jiedu Tablets

Speaking of the medicine Niuhuang Jiedu Tablets, I believe many people are not unfamiliar with it. Because Niuhuang Jiedu Tablets are a must-have household medicine for almost every household. The main function of Niuhuang Jiedu Tablets is to clear away heat and detoxify. It can treat various diseases and symptoms caused by getting angry, such as: swollen and painful gums, swollen and sore throat, inflammation and other symptoms, and the effect is very significant. So what are the ingredients of Niuhuang Jiedu Tablets? Are there any side effects?

The main ingredients of Niuhuang Jiedu Tablets are very many, including bezoar, gypsum, platycodon and other medicinal materials, and it has good detoxification and heat-clearing effects. However, it cannot be taken in large quantities. Taking it in large quantities can easily lead to poisoning and other phenomena. Below I will give you a detailed introduction to Niuhuang Jiedu Tablets.

Niuhuang Jiedu Tablets

Drug ingredients: Niuhuang Jiedu Pills are changed into tablets, which are composed of 8 medicinal herbs including bezoar, realgar, gypsum, rhubarb, scutellaria, platycodon, borneol and licorice.

Preparation method: Realgar is pulverized into extremely fine powder with water; rhubarb is crushed into fine powder; artificial bezoar and borneol are ground into fine powder; the other four ingredients including scutellaria are decocted in water twice, each time for 2 hours, the decoctions are combined, filtered, and the filtrate is concentrated into a thick paste, rhubarb and realgar powder are added, made into granules, dried, and artificial bezoar and borneol powder are added, mixed evenly, and pressed into 1000 tablets (large tablets) or 1500 tablets (small tablets), or coated.

Drug properties: This product is plain tablets or coated tablets. The plain tablets or coated tablets are brown-yellow after removing the coating; they have the aroma of borneol and taste slightly bitter and spicy.

Functions and indications: Clears away heat and detoxifies. It is used for internal heat, sore throat, swollen and painful gums, mouth ulcers, and red and swollen eyes.

Dosage and Administration: Oral administration, 3 small tablets at a time, 2 large tablets at a time, 2 to 3 times a day. It is forbidden for pregnant women to use. Niuhuang Jiedu Tablets (Pills) can be used for treatment but not for conditioning. Conditioning medications generally need to be taken for a long time. The correct way to take Niuhuang Jiedu Tablets is: adults should not take more than 9 small tablets per day, and no more than 6 large tablets per day. Avoid excessive or long-term use. Long-term use may cause addiction. Niuhuang Jiedu Tablets and norfloxacin should not be taken at the same time. Niuhuang Jiedu Tablets can reduce the bioavailability of norfloxacin, thereby reducing its efficacy. Niuhuang Jiedu Tablets are made of bezoar, rhubarb, scutellaria baicalensis, etc. and contain calcium sulfate. When taken together with norfloxacin, the calcium ions and norfloxacin can form a norfloxacin-calcium complex, which reduces the solubility, makes it difficult to be absorbed by the intestines, and reduces the efficacy. The two should not be taken at the same time. If necessary, they can be taken separately after an interval of 2 to 3 hours. Niuhuang Jiedu Tablets are a traditional Chinese patent medicine, composed of bezoar, realgar, gypsum, rhubarb, scutellaria, platycodon, borneol and licorice. It has the effect of clearing heat and detoxifying. It is used for symptoms such as internal heat, sore throat, sore gums, mouth sores, and red and swollen eyes. There will be no side effects if taken correctly under the guidance of a doctor, but long-term and excessive use can cause chronic arsenic poisoning, which is harmful to health and even life-threatening in severe cases, and should attract people's attention.

Precautions

1. Avoid smoking, drinking, spicy and greasy food. 2. Patients with chronic diseases such as hypertension, heart disease, liver disease, diabetes, and kidney disease should take the medicine under the guidance of a physician. 3. If you have 2 to 3 bowel movements per day after taking the medicine, you should reduce the dosage. 4. If symptoms do not improve or worsen after taking the medicine for three days, you should stop taking the medicine immediately and go to the hospital for treatment. 5. Use with caution in children, the elderly and the weak, and those with weak spleen and stomach. Please consult a physician if you need to use it. 6. If you are using other medicines, please consult your physician before using this product. 7. Excessive dosage and long-term use must be done under the guidance of a physician. 8. It should not be used together with cardiac glycosides, alkaloids, antibiotics, isoniazid, vitamin B1 and other drugs. 9. It is not suitable for people with specific or allergic constitution to use.

side effect

1. Allergy and anaphylactic shock; 2. Side effects; 3. Drug-induced liver damage; 4. Thrombocytopenia; 5. Hematuria and epistaxis; 6. Poisoning reaction; 7. Cystitis; 8. Diarrhea; 9. Mental disorder; 10. Addiction. 11. There are reports that oral administration of Niuhuang Jiedu Tablets (Pills) can cause acute gastric mucosal damage, bullous drug eruption, liver damage, and bronchial asthma. 12. The formula of Niuhuang Jiedu Tablets (Pills) contains drugs such as rhubarb, scutellaria, gypsum, bezoar, borneol, etc., which have relatively low toxicity. Only "realgar" is the most toxic and is used in large quantities. Its main ingredient is arsenic disulfide, with arsenic accounting for 75% and sulfur accounting for 24.9%. It is easily decomposed and oxidized when exposed to heat, turning into highly toxic arsenic trioxide, commonly known as arsenic trioxide. 100 mg can cause death. Its toxic effects can affect the nervous system, digestive system, hematopoietic system and urinary system, etc., causing chronic arsenic poisoning. 13. Symptoms of chronic arsenic poisoning: In addition to symptoms such as headache and dizziness, the most prominent manifestation is skin damage, including skin pigmentation, hyperkeratosis, verrucous hyperplasia and skin cancer. Pigmentation is more common on non-exposed areas such as the trunk, buttocks and thighs, appearing as raindrop-like or widespread mottled black or tan spots. There may also be symptoms such as gastrointestinal dysfunction, enlarged liver and numbness of the limbs. In severe cases, there are obvious liver dysfunctions.

Contraindicated drugs

Niuhuang Jiedu Tablets

Drugs that should not be used with Niuhuang Jiedu Tablets (Pills)

Cardiac glycosides: artificial bezoar. Gypsum is rich in calcium ions. If used in combination with cardiac glycosides, it will produce a synergistic effect, enhance myocardial contractility, and may cause arrhythmia and conduction block. Central nervous system depressant: bilirubin contained in artificial bezoar. Bile acid and calcium ions, when used together with central nervous system depressants, can enhance the central nervous system depressant effect. Aminoglycosides: macrolide antibiotics and quinidine. Isoniazid: The rhein and gallic acid contained in rhubarb and the bile acid contained in artificial bezoar can acidify the urine, promote the crystallization of sulfonamide drugs [in] the renal tubules, damage the epithelial cells of the renal tubules and urethra, and thus cause crystalluria. hematuria. Urinary retention and renal damage; aminoglycoside drugs have strong antibacterial ability in alkaline urine, while Niuhuang Jiedu Tablets can acidify urine, resulting in a decrease in its antibacterial ability; artificial bezoar is rich in metal ions such as calcium, magnesium, and iron, which can react with macrolide antibiotics. Quinidine and isoniazid form a poorly soluble complex and affect the absorption of the drug. Vitamin B1 and B6 combined use: the tannin in rhubarb can combine with vitamin B1. b6 forms a complex that is difficult to absorb and is excreted from the body, thus reducing the efficacy of both drugs. Enzyme preparations: Platycodon, Scutellaria baicalensis, and Rhubarb contain glycosides that can hydrolyze the enzyme and cause it to lose its activity; Rhubarb contains a lot of tannins that can form strong hydrogen bonds with the amide bonds and peptide bonds of the proteins in enzyme preparations; the arsenic sulfide in realgar can combine with the sulfhydryl group in the active center of the enzyme, causing the enzyme to lose its activity and affecting the efficacy of enzyme drugs. Aspirin: Antacids: The glucocorticoid substances in licorice can increase gastric acid secretion, reduce gastric mucus secretion, and reduce the resistance of the gastrointestinal mucosa. Combined with aspirin, it can induce. Aggravates the stomach. Duodenal ulcer; combined use with antacids will produce acid-base neutralization, thereby reducing or losing the effect of antacids in treating gastric and duodenal ulcers. Thiazide diuretics: The mineralocorticoid-like substances contained in licorice can promote water secretion. Sodium retention and increased potassium excretion can aggravate thiazide-induced hypokalemia. Hypoglycemic drugs: The glucocorticoid substances in licorice can increase blood sugar, thereby reducing the efficacy of hypoglycemic drugs and may also lead to the risk of worsening of the condition of diabetic patients. Acid salt drugs: The calcium ions contained in them will react with sulfate. Phosphates form precipitates, which reduce the efficacy of acid salt drugs. In addition, the salt components will oxidize the arsenic sulfide in realgar, increasing its adverse reactions. Other Chinese herbal preparations containing arsenic: Realgar is highly toxic and its main ingredient is arsenic disulfide. After arsenic is absorbed through the digestive tract, 80% of the absorbed amount is accumulated in various tissues of the human body. Combining it with arsenic-containing preparations will increase its accumulation and toxicity.

After reading the above detailed introduction about the efficacy and functions of Niuhuang Jiedu Tablets, as well as its ingredients and side effects, I believe that you all already know the benefits and side effects of Niuhuang Jiedu Tablets. Niuhuang Jiedu Tablets are also medicines, and of course they have certain side effects, including allergies, hematuria, poisoning and other symptoms. Therefore, before taking this type of medicine, you must follow the dosage on the instructions. If you don’t understand anything, it is best to consult a doctor in advance before taking the medicine, which will be more helpful for the disease.