The medicinal values of some drugs are similar. In this case, if the medicinal values of the drugs cannot be clearly distinguished, errors will occur when using the drugs. At this time, it is very important to understand the medicinal value of the drug. This situation will directly affect whether the symptoms of the disease can be cured. So what is the medicinal value of Morinda officinalis? Let’s talk about it now. 1. Weight-increasing and anti-fatigue effects: Male Kunming mice weighing 16-18g were selected and divided into 4 groups according to their weight. The blank group was gavaged with 20ml/kg of distilled water every day, and the drug-treated group was gavaged with 20ml/kg of Morinda officinalis decoction for 11 consecutive days. Each group took the medicine once before the experiment. Five mice were placed in each swimming test, and they were weighed before the experiment and loaded with 5% of their actual weight. The results showed that Morinda officinalis could significantly increase the body weight of mice and prolong their continuous swimming time. 2. Effect on immune function: The ACTH bioactivity test was performed on underage mice for 4 days. The results showed that oral administration of 65g/(kg.d) and 80g/(kg.d) of Morinda officinalis warm infusion and 60g/(kg.d) of Morinda officinalis 50% ethanol extract could cause thymus atrophy in mice (P values were P < 0.05, p < 0.001, and p < 0.001, respectively). Intraperitoneal injection of 10g/(kg.d) of Morinda officinalis warm infusion also caused significant thymus atrophy in mice (P < 0.001). According to the method reported by Qiao Zhisheng, 21-day-old Kunming mice were selected, both male and female, and blood was separated according to body weight. The positive control group was gavaged with 0.6 ml of 0.2% (g/ml) vitamin B4 solution per mouse every day, and the medication groups were given Morinda officinalis decoction for 10 consecutive days. 24 hours after the last dose, the body weight was weighed, blood was taken from the tip of the tail, the number of white blood cells was counted, and the animals were killed. The thymus was separated and weighed. The results also proved that Morinda officinalis has the function of inhibiting thymus atrophy in mice and increasing the number of white blood cells in their blood. 3. Effects on accessory sexual organs: Oral administration of crude extract of Morinda officinalis to rats or mice for 14-15 consecutive days showed no anabolic effect (increase in body weight, levator ani muscle or glomus cavernosum muscle weight, or mouse kidney weight) and no androgenic effect (increase in seminal vesicle weight as an indicator). 4. Effect of promoting corticosterone secretion: ICR male mice weighing about 35g were used to measure the amount of corticosterone in the blood according to the Diamondstone method. The water extract of Morinda officinalis (1g/kg) was orally administered. The results showed that the activity of the glucocorticoid enzyme marker liver AIP was significantly increased, and intraperitoneal injection also showed more TAT (tyrosine aminotransferase) activity, indicating that the extract of Morinda officinalis has the effect of increasing the level of corticosterone in the blood, and its activity may be due to the stimulation of the pituitary-adrenal cortex system. After figuring out the specific medicinal value of Morinda officinalis, you can use it safely. This way, it won’t cause anything bad to your body. When using the drug, if it is used together with other drugs, it is best to be treated under the guidance of a doctor. This will achieve better treatment results. |
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