What are the effects and functions of licorice

What are the effects and functions of licorice? I can give you the following introduction. Let everyone have an intuitive understanding of licorice. Licorice's benefits include treating coughs, stomach ulcers, mouth ulcers, ileitis, leaky gut syndrome, irritable bowel syndrome, and Crohn's disease. Today, licorice extract is available in both solid and liquid forms. Its main ingredient is glycyrrhizic acid, which is also the reason why licorice tastes sweet. These are the functions and effects of licorice.

1. Detoxification effect: Glycyrrhizin or its calcium salt has a strong detoxification effect on diphtheria toxin and tetanus toxin. It also has a detoxification effect on some allergic diseases, experimental hepatitis in animals, pufferfish poison and snake venom. Its detoxification mechanism may be multifaceted, through physical and chemical precipitation, adsorption and combination, it strengthens the liver's detoxification function, and the hydrolysis product of glycyrrhizin, glucuronic acid, is also an effective ingredient for detoxification.

2. Anti-inflammatory and anti-allergic reactions: Glycyrrhetinic acid has an inhibitory effect on cotton ball granuloma, formaldehyde edema, tuberculin reaction, and subcutaneous granuloma cystic inflammation in rats. Ammonium glycyrrhizinate and sodium glycyrrhizinate can effectively affect the exudative and proliferative phases of subcutaneous granulomatous cystic inflammation, and the intensity of their effect is weaker than or close to that of cortisone. Among the various preparations of glycyrrhizic acid, succinate has the highest anti-inflammatory activity, but is also highly toxic. The mechanism of licorice's anti-inflammatory and anti-allergic effects has not yet been fully elucidated.

3. Licorice has an expectorant effect and can promote the secretion of the throat and bronchi, making it easier to cough up phlegm.

4. Glycyrrhizic acid derivatives have significant antitussive effects on experimental cough in guinea pigs and cats.

5. Various preparations of licorice have a significant inhibitory effect on experimental gastric ulcers in rats. The water extract of licorice can protect the gastric mucosa and treat gastric ulcers. According to observations from clinical and pharmacological research laboratories, licorice water extract can increase the "glycosamine" component of gastric mucosal cells, thereby protecting the gastric mucosa from damage.

6. Effect on gastric juice secretion: After intragastric administration, licorice fluid extract can absorb gastric acid, thus reducing gastric acid concentration, but it can also play a role after absorption. It also has an inhibitory effect on basal secretion.

7. Antispasmodic: Licorice decoction and fluid extract have inhibitory effects on isolated animal intestines, and have antispasmodic effects on intestinal spasms caused by acetylcholine, barium chloride, histamine, etc. Licorice has a relaxant effect on both the isolated intestines and the stomachs of animals in vivo.

8. Licorice can significantly reduce liver degeneration and necrosis in animals with experimental liver damage, and the content of glycogen and ribonucleic acid accumulated in liver cells is mostly restored or close to normal, and the activity of serum alanine aminotransferase is significantly reduced, indicating that licorice has the effect of resisting liver damage.

9. Adrenal cortex hormone-like effect: Licorice can reduce urine volume and sodium excretion, increase potassium excretion, increase blood sodium, reduce blood calcium, and atrophy the zona glomerulosa of the adrenal cortex in many animals. Licorice can increase the excretion of free 17-hydroxycorticosteroids in urine and reduce the bound form. Small doses can cause thymic atrophy, increased adrenal weight, widening of the fasciculate layer, and decreased adrenal vitamin C content. Licorice can significantly enhance and prolong the effects of cortisone. Regarding the principle of licorice producing adrenal cortical hormone-like effects, some people believe that the chemical structure of glycyrrhizic acid is similar to that of adrenal cortical hormones, and the effects are also similar, which is a direct effect; others believe that it is an indirect effect, that is, glycyrrhizic acid inhibits the destruction of adrenal cortical steroids in the body, so the level of corticosteroids in the blood increases accordingly, showing a more obvious adrenal cortical hormone-like effect.

10. Licorice has the effect of counteracting acetylcholine and can enhance the cardiotonic effect of adrenaline.

11. Anti-cancer: Glycyrrhizic acid has an inhibitory effect on experimental myeloma and ascites liver tumor in rats. It has an inhibitory effect on Ehrlich ascites carcinoma in mice.

12. The combined use of licorice and Daphne genkwa has opposite effects: the toxicity of the co-immersion group was significantly higher than that of the separate immersion group. The diuretic and laxative effects of Daphne genkwa and licorice were inhibited when they were used together, which can enhance the toxicity of licorice.

The above are some solutions to the effects and functions of licorice. I hope everyone can find a method that suits them and can correctly solve their own symptoms. What are the functions and effects of hay? Everyone has their own understanding of this problem, and you can find a way to solve the problem through the above methods! !