Why does this "rich disease" prefer men?

In addition to humans, primates, birds and reptiles also suffer from gout in nature. People have even found traces of tophi in Tyrannosaurus Rex fossils. However, other mammals do not have the trouble of gout because they have uricase in their bodies, which can reduce uric acid to allantoin and excrete it out of the body.

Recently , Japanese researchers found that drinking coffee every day can reduce the risk of gout by about 25%. In fact, similar research has existed for a long time. In 2007, a US study showed that drinking 4 cups of coffee a day can reduce the risk of gout by 40%. Drinking more than 6 cups of coffee can reduce the risk of gout by 60%.

Currently , most studies believe that the reason why coffee can reduce the risk of gout may be related to caffeine and polyphenols. Caffeine is a methylxanthine base that can block the action of xanthine oxidase in the body and reduce the production of uric acid. In addition, caffeine is also a weak diuretic that can promote the excretion of uric acid. Chlorogenic acid in polyphenols can increase insulin sensitivity and reduce insulin levels, thereby indirectly promoting the elimination of uric acid.