The efficacy and function of Xue San Shu

There are many types of Chinese medicine. When we choose, we need to understand the medicine first. So do you know about the medicinal material Xue San Shu? Let us introduce it below.

[Other names] Sweet Tung, A Drop of Blood, Mountain Turtle, Single-legged Sapium.

[Source] Medicinal material source: The tuberous root of the plant Cyperus rotundus of the Menispermaceae family.

[Original morphology] The blood-scattered potato is a perennial herbaceous vine, and the whole plant is hairless. The tuber is nearly oblong spindle-shaped or irregularly lumpy, often exposed on the ground, with a diameter of 10-15cm, brown and rough outer skin with many warty papillae, the stem is often purple-red, and red juice flows out when the branches and leaves are broken. Leaves are alternate and papery; petiole is equal to or slightly longer than leaf blade, and peltate near the base of petiole; leaf blade is broadly triangular-ovate, 6-12cm long and wide, with a small tip, base truncate or nearly rounded, sometimes slightly cordate, entire or sometimes with several irregular coarse teeth. The umbels are axillary and dioecious; the male inflorescence is compound umbel, the cymes have obvious stalks, loosely clustered at the end of the pseudocyme, the sepals and petals are purple, the petals are shell-like, concave, without glands on the inner surface, and the stamens and filaments are fused into a column; the female inflorescence is capitate, the pseudocyme is not visible during flowering, the perianth is bilaterally symmetrical, with 1 sepal and 2 petals. The drupe is small, with an endocarp no longer than 10 cm, and the carvings on it have hooked ends. The flowering period is from May to July, and the fruiting period is from July to August.

[Habitat distribution] Ecological environment: grows in valleys, stream banks, forests, rock crevices and cliffs.

[Properties] 1. Identification of properties: The tuber is slightly oblate or spherical, with a diameter of 6-13cm, a slight depression at the top, and the remaining stem base is 5-7cm in diameter. The surface is dark brown, rough, with longitudinally protruding lenticels, 1-3mm long. Most of the products are circular sulfur-cut slices with a diameter of 3-7cm, a thickness of 2-5mm, and slightly curled. The cross section shows the vascular bundles (ternary structure) arranged in 3-4 concentric rings. It has a faint smell and a bitter taste.

【Chemical composition】 Xue San Shu contains crebanine, sinoacutine, stephanine, dehydrostephanine, xylopinine, teirahydropalmatine, isotetrandrine, cepharanthine, homoaromoline and berbamine and other bioalkaloids.

[Pharmacological Action] At the animal tolerance dose, Stephania quinata has a certain degree of inhibitory effect on mouse transplanted sarcoma S180, with an inhibition rate of 16%-34%; it has a significant inhibitory effect on rat transplanted carcinosarcoma W256, with an inhibition rate of 31.3%-64%.

[Identification] Physical and chemical identification (1) Take 1g of crude powder of this product, add 10ml of ethanol, soak overnight and filter. The filtrate was evaporated to dryness, and the residue was dissolved in 4 ml of dilute hydrochloric acid and filtered. Take 1 ml of the filtrate and add 2 drops of improved potassium bismuth iodide test solution to produce an orange precipitate; add 2 drops of potassium mercuric iodide test solution to produce a large amount of yellow-white precipitate (check for bioalkali) (2) Place a fresh section of a piece of this product under ultraviolet light (254 nm) for observation. The outer side appears yellow and the middle part appears light blue-purple.

【Nature and flavor】 Bitter; Cold

【Functions and indications】 Clears away heat and detoxifies; disperses blood stasis and relieves pain. Mainly used for upper respiratory tract infection, pharyngitis, carbuncle, stomachache, gastroenteritis, toothache, neuralgia, traumatic injury

[Usage and Dosage] For oral use: decoction, 6-15g. For external use: take appropriate amount and mash fresh product for application.

【Note】 Pregnant women should not take this medicine.

[Clinical application] Qiangui Qianjinteng injection contains 15 mg of total alkaloids of Qiangui Qianjinteng, which is made into 1000 ml of injection. Take the crude powder of Qiangui Qianjinteng and percolate it with 80% ethanol according to the percolation method, recover the ethanol from the percolated liquid and concentrate it to obtain an extract, add 10% sulfuric acid to dissolve, adjust the pH to 1-2, refrigerate, filter, extract the filtrate with chloroform several times, discard the chloroform layer, add concentrated ammonia water to the acid water layer to adjust the pH to 9, extract with chloroform, recover the chloroform, evaporate to dryness to obtain total biological alkali, add potassium hydroxide methanol solution, adjust to pH 11, add iodomethane (1:1) and reflux for 1 hour, recover methanol, evaporate to dryness in a water bath to obtain total alkali iodide methyl quaternary ammonium salt, add an appropriate amount of water for injection, adjust the pH to 3.5 with dilute hydrochloric acid, add 0.2% activated carbon, boil, filter, add water for injection to the filtrate to the full amount, fine filter, encapsulate, and sterilize. This product is a yellow-brown clear liquid. Take this injection solution and evaporate it in a water bath, add anhydrous ethanol to dissolve it, filter it, evaporate the ethanol, and then dissolve it in water for the following test: adding silver nitrate test solution to the aqueous solution produces a light yellow precipitate; adding potassium bismuth iodide test solution to the aqueous solution produces a reddish brown precipitate. Function: It is a neuromuscular blocking drug and has a relaxant effect on skeletal muscle. Used as an adjuvant for general anesthesia. Intravenous injection. Dosage for combined use with Chinese anesthesia: 0.11-0.45 ml/kg; Dosage for combined use with acupuncture anesthesia: 0.23-0.4 ml/kg. Add 20 ml of 5% glucose during use. Push injection speed: 2-4 minutes [Chinese Herbal Medicine Newsletter, 1978, (4): 28]

【Excerpt】 Chinese Materia Medica

Above we introduced what blood yams are. We know that blood yams have very comprehensive effects and functions, so we can use blood yams as a means of regulating the body in daily life.