Nowadays, due to the occurrence of many diseases, there are also many drugs that can be used for proper treatment. Oleanolic acid tablets are a common auxiliary treatment drug for liver disease. Many patients can take this type of drug according to the doctor's prescription during the treatment after consulting a doctor. This kind of drug is an oral anti-tumor auxiliary drug and a drug that enhances the body's immunity. It can reduce liver damage because the oleanolic acid contained in the fruit acid tablets is very helpful for liver disease, lowering serum blood sugar and promoting the growth of liver cells. So what are the main pharmacological effects of oleanolic acid? Oleanolic acid tablets are mainly used as an auxiliary anti-tumor drug and an auxiliary treatment for liver disease to enhance the body's immunity. It has a certain protective effect on the body, which can not only improve the regeneration of liver cells but also accelerate the repair of necrotic tissue. 1. Reduce liver damage: Oleanolic acid is a pentacyclic triterpenoid compound that has a significant protective effect on acute and chronic liver damage in rats induced by carbon tetrachloride. After treatment, the enlarged mitochondria and dilated rough endoplasmic reticulum were restored. It can also significantly reduce ballooning degeneration, necrosis and inflammatory response of hepatocytes in acute and chronic liver damage. The accumulation of triglycerides in the liver decreases and the amount of glycogen increases. 2. Reduce serum alanine aminotransferase activity: Oleanolic acid has a significant enzyme-lowering effect on animals with acute and chronic hepatitis and cirrhosis. 3. Reduce serum r-globulin, which is consistent with the reduction of liver-related inflammatory response seen in histological observations. 4. Promote the regeneration of liver cells: Oleanolic acid can significantly increase the number of nuclear division phases in the residual liver of rats, and the regeneration degree is higher than that of the control group, indicating that it has the effect of promoting cell regeneration. 5. Reduce the level of tyrosine in brain homogenate of rats with liver cirrhosis: Since the level of tyrosine in brain homogenate is significantly reduced, it can inhibit the formation of false neurotransmitters, so it is beneficial to the prevention and treatment of hepatic encephalopathy. 6. Inhibition of liver fibrosis: In rats with liver fibrosis treated with oleanolic acid, liver fibrosis was severe and significantly alleviated, and the liver collagen content was reduced, suggesting that it has the effect of preventing and treating liver cirrhosis. 7. Oleanolic acid has a significant inhibitory effect on the mononuclear phagocyte system, macrophage phagocytic function and experimental arthritis of mice, but has an effect on heterosexual humoral immune function and antigen-binding cells. Enhance immunity and inhibit the growth of S180 tumor strain. 8. It has a protective effect on chromosome damage, a preventive effect on experimental atherosclerosis, and can also correct protein metabolism disorders. The above are the pharmacological effects of oleanolic acid tablets. It can not only reduce liver damage, but also reduce the activity of serum alanine aminotransferase, reduce serum R globulin and promote liver cell regeneration, reduce the level of tyrosine in cirrhotic rats, and can be beneficial for the prevention and treatment of liver disease and encephalopathy. It can also promote fiber proliferation and has many therapeutic effects on the repair of necrotic cells. If children with liver disease use this drug, they should consult a doctor or pharmacist in time. If adverse effects occur due to overdose, they should seek medical attention in time. |
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