Effects of Millettia reticulata

Millettia reticulata is a less common medicine, and it can be used to treat many types of diseases. Moreover, the uses of Millettia reticulata are quite extensive, so when you are learning about it, you should have a good understanding of it so that you can use it. There will be no harm to your own health. What are the effects of Millettia reticulata? Such medicine is very helpful for activating blood circulation in the human body.

What are the specific effects of Millettia reticulata? It is very helpful in regulating common female diseases, especially in treating female menstrual disorders, so you can choose it with confidence.

Chicken Bloodvine Effects:

Nature and flavor: bitter, sweet, warm. It enters the liver and kidney meridians.

Functions and indications: Nourishes blood, promotes blood circulation, and dredges meridians. Used for irregular menstruation, blood deficiency, chlorosis, numbness and paralysis, and rheumatic pain. Function: The bark fiber can be used as raw material for artificial cotton, papermaking and weaving; the vine is used for medicinal purposes, and has the effects of promoting qi, supporting wind and activating blood circulation; the root is used as medicine, and has the function of relaxing muscles and activating blood circulation, and also has the effect of killing insects. The vines and roots contain phenolic components, amino acids, sugars and resins. Efficacy: Promote blood circulation and relax muscles; nourish blood and regulate menstruation. Indications: numbness of hands and feet; paralysis of limbs; rheumatic pain; irregular menstruation in women; dysmenorrhea; amenorrhea.

Pharmacological effects of Millettia reticulata

1. Effect on the hematopoietic system: According to He Shuma et al., the decoction of the dense-flowered bean vine (100%) has a blood-tonifying effect on experimental rabbit anemia, which can increase blood cells and hemoglobin. It has a stronger effect than that of Millettia odorata. In 1989, Zhang Shufang et al. reported that Millettia reticulata decoction (2 g/kg) had no significant effect on the recovery of peripheral cells, hemoglobin and reticulocytes in rabbits with hemorrhagic anemia: the experiment used 7 litters of rabbits, 5 of which had 4 rabbits each, and the remaining 2 litters had 2 rabbits each, for a total of 24 rabbits. There are 13 females and 11 males, weighing 1.42-2.58kg. Four rabbits from the same litter were randomly divided into three groups: Danshen, Angelica, Millettia reticulata, and a control group, with 5 rabbits in each group. The normal values ​​were only observed for the other 4 mice. During the experiment, blood was collected from the ear vein at 8:30 am every day (after the first feeding) to measure hemoglobin, red blood cell count, and reticulocyte count. After the values ​​of the three indicators became constant, they were measured continuously for 3 days and used as the normal values ​​for the rabbit. Starting from the 4th day, blood was let out from the V-shaped incision at the tip of the rabbit's ear at 8:30 am every day. Once a day for 3 consecutive days, each bloodletting is equivalent to 1% of the body weight on that day, and the total bloodletting volume is equivalent to 50% of the total blood volume. After bloodletting, 5% glucose solution was gavaged to replenish lost body fluids, with the dosage being 1% of body weight. Starting from one day after the bloodletting, each group was gavaged with 20% decoction of Salvia miltiorrhiza, Angelica sinensis, and Millettia reticulata at a dose of 2 g per 1 kg body weight. The other group was given 10 ml of normal saline per 1 kg body weight as a control, once a day for 10 consecutive days. Blood was drawn from the ear vein at 8:30 am every day from 1 to 13 days and on days 16, 18, and 21 after the bloodletting to check the blood count. Taking the red blood cell count and hemoglobin value before bloodletting as 100%, the average number of days for each group of rabbits to recover to 95% after bloodletting are shown in Tables 1 and 2 respectively; taking the normal value of reticulocytes before bloodletting as 100%, the peak time of reticulocytes after bloodletting and its level 21 days later are shown in Table 3. The above results show that Millettia reticulata has no significant effect on the recovery of red blood cells, hemoglobin and reticulocytes in the ear vein of rabbits with hemorrhagic anemia.

2. Effects on coagulation and fibrinolysis: In the experiment on the effects on the coagulation and fibrinolysis process of canine blood in vitro, the femoral artery was exposed after anesthesia, and blood was collected (the test tube was placed in ice immediately after blood collection). 1 part of anticoagulant (sodium oxalate, sodium citrate) was added to 9 parts of whole blood, and the plasma was separated by centrifugation. The plasma was divided into 3 parts, and 0.03 ml of normal saline, salvia miltiorrhiza injection, and millettia spatholobi injection were added to each of them. Determine the recalcification time (reflecting the intrinsic coagulation process), prothrombin time, thrombin coagulation time, plasma fibrinogen quantification and globulin lysis test. It can be seen that Millettia reticulata (containing 3 mg of crude drug per 1 ml) has no obvious effect on the coagulation and fibrinolysis process of isolated dog blood.

3. Inhibitory effect on the heart and lowering blood pressure: 50% Millettia reticulata decoction has a slight inhibitory effect on the isolated and in vivo hearts of toads. Administration of 0.43-0.5g of the herb/kg decoction to anesthetized rabbits and 0.3g of the herb/kg decoction to dogs can cause a drop in blood pressure; however, it has a constrictive effect on isolated rabbit ears and toad blood vessels.

4. Anti-cancer effect: In vitro test dose of 500 micrograms (hot water extract)/ml, the inhibition rate of JTC-26 was 94.4%; phage method was used to screen anti-tumor drugs, and this product had anti-phage effect.

5. Regulation of lipid metabolism: Japanese quail were gavaged with 6g/kg of Millettia reticulata decoction for 14 days and 47 days, which could increase HDL2-C, reduce HDL3-C, and increase the ratio of HDL2-C/HDL3-C. This ratio is an important indicator for evaluating lipid metabolism and arteriosclerosis.

Through the above introduction, we have some understanding of the efficacy of Millettia reticulata, and its effects are also explained in detail. Such medicines have many effects, especially they are very helpful in improving human metabolism problems, so you can use it with confidence.