Nine functions and effects of Citrus aurantium you must know

When it comes to Citrus aurantium, many people may ask what it is. It is a Chinese medicinal material, which is divided into many different types, including green-skinned Citrus aurantium, fragrant round Citrus aurantium, etc. It can be used in combination with other Chinese medicinal materials to treat superficial gastritis, ulcers, cough, etc. It can be said that Citrus aurantium has many effects and functions. Now, experts will give us a detailed introduction to the effects and functions of Citrus aurantium.

Citrus aurantium is a plant that can be used as both medicine and food. It can be used to treat many diseases and has a good therapeutic effect on indigestion, uterine prolapse, etc. Of course, the effects and functions of Citrus aurantium are more than that. If you want to know more, you can continue to read the content of this article.

The efficacy and function of Citrus aurantium:

It is bitter and sour in nature, and slightly cold in nature. It enters the lung, spleen, liver, stomach and large intestine meridians. Functions and indications: chest fullness, flank pain, indigestion, abdominal distension, heaviness after diarrhea, rectal prolapse, and uterine prolapse.

1. Increase coronary blood flow and renal blood flow, and reduce myocardial oxygen consumption

2. Intravenous injection of 0.02-0.5 mg/kg in anesthetized dogs showed a pressor effect. Large doses produced significant pressor effects. Intravenous infusion of 0.2 mg/kg per minute will increase renal blood flow by 75% and double urine volume. It has a strong effect of inducing myocardial rhythm, which is comparable to that of adrenaline and stronger than dopamine and synephrine. Synephrine contained in Citrus aurantium is an adrenaline a-receptor stimulant and also has a certain stimulating effect on cardiac B-receptors. It constricts blood vessels and increases blood pressure.

Effects on blood flow to the heart, brain, kidneys, etc.

3. Intravenous injection of 1 ml/kg of Zhishi injection (each 1 ml = 4 g of raw medicine) into anesthetized dogs has a significant effect in increasing cerebral blood flow. After injection, cerebral blood flow increased by an average of 82.6±20.56ml/100g brain weight/minute (P<0.01). The average increase was equivalent to 86.4% of the cerebral blood flow before injection. The average cerebral vascular resistance index decreased by 0.428±0.12 (P<0.01), which had a significant effect in reducing cerebral vascular resistance. Intravenous drip of 1.5 ml/kg had no significant effect on cerebral blood flow. Intravenous injection of 1.5 ml/kg of Zhishi injection in anesthetized dogs significantly increased renal blood flow, with an average increase of 64.5±9.4 ml/100 g kidney weight/minute (P<0.01), and the average increase was equivalent to 53.9% of the renal blood flow before injection. The renal vascular resistance index decreased by an average of 0.519±0.176 (P<0.05), which significantly reduced renal vascular resistance. However, the same dose of intravenous drip had no obvious effect. After intravenous injection of the above dose, blood pressure increased and femoral artery blood flow decreased, with an average decrease of 41.3% before medication, and vascular resistance also increased.

4. Diuretic effect

5. Intravenous injection of Zhishi injection and N-methyltyramine in dogs can significantly increase urine volume, while blood pressure and renal vascular resistance are significantly increased. Its diuretic effect may be produced by inhibiting tubular reabsorption and other effects. Other studies believe that Zhishi exerts its sodium excretion and diuretic effects by strengthening the heart, constricting renal blood vessels, and increasing filtration pressure.

6. Effects on gastrointestinal smooth muscle

7. The decoction of Zhishi showed an inhibitory effect on part of the isolated intestinal tract of mice, while it showed an inhibitory effect on the entire isolated intestinal tract of rabbits. This effect can be antagonized by acetylcholine. However, when 100% Citrus aurantium was gavaged into the stomach of dogs with gastric and intestinal atrophy, it had a stimulating effect and could increase the rhythm of gastrointestinal motility and contraction. When dogs were gavaged with 100% concentrated Zhishi liquid at 1 ml/kg, it was found that the period and phase I duration of the interdigestive period integrated electromyography of the small intestine were shortened, while the phase II duration was prolonged. This shows that Citrus aurantium can enhance the tension and phase contraction function of small intestinal smooth muscle.

8. Effect on uterine smooth muscle

9. The decoction of Zhishi has a significant excitatory effect on the isolated uterus of non-pregnant and pregnant rabbits, the uterus in situ and uterine impotence of non-pregnant rabbits, and can increase the rhythm of uterine contraction. However, it has an inhibitory effect on the isolated mouse uterus, whether pregnant or non-pregnant.

After reading the above experts' introduction, I believe everyone has some knowledge and understanding of the effects and functions of Citrus aurantium. Since Citrus aurantium is a traditional Chinese medicine, it is best to use it under the guidance of a doctor, because Chinese medicine emphasizes dialectical use of medicines, and reasonable combinations are needed to achieve good results in treating diseases.