What are the effects and functions of Sophora flavescens?

Sophora flavescens is a traditional Chinese medicinal material belonging to the legume family. It can be picked in the wild in spring and autumn. After picking, you can remove the roots, slice them and dry them. Don't underestimate this Chinese herbal medicine. Sophora flavescens actually plays a very powerful role in life. Its extract, sophora flavescens alkaloid, is also used in life and treatment. So, what are the effects and functions of sophora flavescens alkaloid?

Sophora flavescens

[Plant source]. This product is a bioalkaloid extracted from the fruit or aerial parts of Sophora alopecuroides, a plant of the genus Sophora in the family Leguminosae.

[Alias] Matricaria, a-Sophora flavescens, cis-matrine

[Molecular formula and molecular weight] C15H24N2O; ;248.36

[Physical properties] This product is white needle-shaped crystal or crystalline powder; odorless, bitter taste; it is hygroscopic when exposed to air for a long time.

And turns light yellow. This product is very soluble in ethanol, chloroform, toluene, benzene, easily soluble in acetone, and soluble in water.

Slightly soluble in hot water and petroleum ether.

[Pharmacological action]

1. Anti-cancer: It is effective against Ehrlich ascites carcinoma in mice both in vivo and in vitro, and has a significant inhibitory effect on S180. The therapeutic index is relatively high, about 1/30 and 1/60.

2. Toxicity: LD50 is 150 mg/kg for intraperitoneal injection in mice and 125 mg/kg for intraperitoneal injection in rats.

3. Clinical: It has certain efficacy in treating cervical cancer, gastric cancer, liver cancer and gallbladder cancer.

Efficacy and Use

Modern scientific research shows that Sophora flavescens extract has the following effects:

Beauty and skin care effects

It is cold in nature, has the effects of clearing away heat, drying dampness, and killing insects. Sophora flavescens bath can clear away dampness and heat in the lower abdomen, kill insects and relieve itching, and has a good effect on relieving skin itching. Plant Chinese herbal medicine can balance oil secretion, dredge and astringe pores, remove toxins and impurities in the skin. The rich herbal nutrition promotes the growth and repair of damaged blood vessel nerve cells, restores the vitality of subcutaneous capillary cells, and makes the skin firm and smooth again, playing a role in beauty and skin care.

Whitening effect

Total Sophora flavescens alkaloids and oxymatrine have obvious white blood cell increasing effects and have obvious therapeutic effects on leukopenia caused by cyclophosphamide, X-ray and cobalt ray irradiation.

Anti-inflammatory effects

Sophora flavescens has an inhibitory effect on the ear swelling caused by croton oil in mice, the increased peritoneal exudation in mice caused by acetic acid, and the carrageenan-induced foot pad swelling in rats.