What are the effects of salvianolic acid salt?

The busy pace of modern life has caused many people to have abnormal physical conditions and health problems. Among them, various heart diseases and circulatory system diseases have had a great impact on the lives of patients. Among them, heart disease is the most harmful and the most uncertain. There are many drugs for treating heart disease, and people should choose according to their own condition. For example, what is the effect of salvianolic acid salt?

effect:

Salvia miltiorrhiza polyphenols can promote blood circulation, remove blood stasis and unclog meridians. It is used for stable angina pectoris in coronary heart disease, which is graded as I and II. The symptoms of angina pectoris are mild or moderate. The TCM diagnosis is that of blood stasis in the heart, with symptoms such as chest pain, chest tightness and palpitations.

Pharmacology and Toxicology:

Pharmacological experiments show that this product can reduce the degree of ST segment elevation on the electrocardiogram, reduce the infarct area, and reduce serum LDH in dogs with acute myocardial infarction caused by coronary artery ligation; it has a certain inhibitory effect on ADP-induced platelet aggregation in rats.

It has a certain inhibitory effect on arteriovenous bypass thrombosis in rats.

Toxicological tests showed that in the 30-day long-term toxicity test on dogs, the hepatocytes and renal tubular epithelial cells of the high-dose group (320 mg/kg) contained bilirubin and brown-yellow drug-like substances. Macrophages engulfing the drug-like substances were seen in the lung and spleen tissues, the cortical and medullary sinuses of the mesenteric lymph nodes, and the intestinal mucosa, and the above organs were also brown-brown. There was mild hyperplasia of the bone marrow hematopoietic tissue, and yellow drug-like substances were occasionally seen. The vascular endothelial cells at the injection site were damaged, fresh thrombi were formed in the blood vessels, and some thrombi were organized.

Adverse reactions and precautions:

A small number of patients experience dizziness, headache, and headache. Occasionally, some patients may experience mild headaches during infusion due to the rapid rate of intravenous drip. Occasionally, serum alanine aminotransferase increases, which disappears after drug discontinuation.

Contraindications: Use with caution in patients with bleeding tendency. Use with caution in pregnant or lactating women.

Dosage and Administration:

Intravenous drip. Take 200 mg at a time, dissolve in 250ml - 500ml of 5% glucose injection solution before use. Once a day. The treatment course is 2 weeks.

Adverse reactions:

1. A small number of patients experience dizziness, vertigo, and headache.

2. Occasionally, some patients may experience mild headaches during infusion due to the rapid drip rate.

3. Occasionally, blood alanine aminotransferase may increase, which disappears after drug withdrawal.