How does Cornus officinalis lower blood sugar?

Only a few people know that Cornus officinalis has anti-diabetic effects, and that Cornus officinalis alcohol extract has a significant blood sugar-lowering effect on alloxan- and adrenaline-induced diabetic rats. However, it had no significant effect on the blood sugar of normal rats, suggesting that Cornus officinalis has a certain therapeutic effect on patients with insulin-dependent diabetes. Let’s take a brief look at how Cornus officinalis can lower blood sugar.

1. Cornus officinalis polysaccharide has a significant effect on promoting immune response, activating natural killer cells (NK) and macrophage systems, stimulating the secretion of interleukin-1 (IL-I), tumor necrosis factor (TNF) and 7-interferon (IFN), and regulating the production of interleukin-2 (IL-2). 2.5mg/ml can increase lymphocyte transformation by 90%.

2. Anti-inflammatory effect: Cornus officinalis polysaccharide has a significant analgesic effect on pain reactions caused by heat and chemical stimulation, and has a significant inhibitory effect on acute and chronic inflammatory reactions; it has an inhibitory effect on capillary permeability.

3. Antibacterial effect: The antibacterial activity of Cornus officinalis extract was tested against several common food microorganisms. The results showed that the extract of Cornus officinalis had significant antibacterial effect on bacteria and some yeasts.

4. Hypoglycemic effect: Cornus officinalis has the effect of treating diabetes. Cornus officinalis alcohol extract has a significant hypoglycemic effect not only on diabetic rats induced by adrenaline or alloxan, but also on diabetic rats induced by streptozotocin, but has no significant effect on the blood sugar of normal rats. The active ingredients of Cornus officinalis that have the effect of lowering blood sugar are ursolic acid and oleanolic acid.

5. Effects on vascular endothelial cells and cardiomyocytes: The active ingredients of Cornus officinalis can counteract the morphological changes of cardiomyocytes caused by hyperglycemia, improve cell survival rate, and increase the superoxide dismutase activity of cardiomyocytes damaged by blood sugar, reduce the content of malondialdehyde, a product of lipid peroxidation reaction, and the exudation of lactate dehydrogenase and aspartate aminotransferase.

6. Antiarrhythmic effect: In the study of the antiarrhythmic effect of Cornus officinalis, it was found that the total extract of Cornus officinalis, ethyl acetate extract and the residual extract of Cornus officinalis all have very obvious antiarrhythmic effects. Its antiarrhythmic effect may be related to prolonging the myocardial action potential, increasing the absolute value of the resting potential and reducing the automaticity of the sinoatrial node.

The above is a relatively detailed answer to the question of whether Cornus officinalis can lower blood sugar. The content described above can help everyone solve the problem. Many times, we need to maintain good living and eating habits in our daily lives, which is the guarantee of our health. Don't eat spicy or irritating things as this will increase the burden on our body. You need to exercise moderately on a regular basis.