Can Agrimony be taken for a long time?

Herba Centifoliae is a Chinese herbal medicine that has a good therapeutic effect on malaria, fatigue, carbuncle, hemoptysis and hematemesis. The astringent and hemostatic effect of cranesbill is very good. It can have a good therapeutic effect on some bleeding symptoms. Therefore, when there is bleeding in the body, you can use cranesbill to treat it. So can cranesbill be used for a long time? Let us give you a detailed introduction below.

All medicines are toxic, and long-term use is not recommended.

1. Hemostatic effect Modern pharmacological research results have not yet determined whether crane grass can stop bleeding. It has been reported that after intravenous injection of crane grass suline, the bleeding time of mice was shortened by 45%. Intravenous injection of crane grass sodium salt 2mg/kg to 104 rabbits increased the number of platelets, increased serum calcium content and shortened coagulation time. Crane grass powder is used for traumatic bleeding, bleeding or oozing during visceral surgery, and has a positive effect. There are also reports that the infusion of this product and the crane grass injection have no effect on promoting blood coagulation, whether in vitro or in vivo experiments.

2. Antibacterial and anti-inflammatory effects Experiments have shown that the hot water or ethanol extract of Agrimoniae has an inhibitory effect on Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Shigella flexneri and Salmonella typhi in test tubes, and also has an inhibitory effect on human tuberculosis. The water extract and water-alcohol extract of the whole plant have an anti-inflammatory effect on conjunctivitis in rabbits caused by mustard oil or staphylococcal infection. This effect is related to the tannins in Agrimoniae that can generate condensed tannic anhydride (Phlobaphene).

3. Insecticidal effect: Atropol has a definite insecticidal effect on the cysticercosis, larvae, Morse's worm and short-shelled worm of the pork worm. The speed of Atropol's killing worms is much faster than that of Miexing. Experiments have shown that the insect-repelling effect of Atropol is not through the nervous system, but a direct contact killing effect on the entire worm body. Whether it is the head and neck chain, the egg-carrying segment chain or any part of the worm body, all parts that come into contact with Atropol will contract and die, while the parts that do not come into contact with the liquid medicine will survive as usual. There are reports that after the whole worm or the separated segment of Morse's worm body is blocked by atropine, the effect of acetylcholine can be blocked by atropine, but it does not affect the effect of Atropol on the worm body, which shows that the direct contact effect of Atropol on the worm body may not be through the choline receptor. Experiments have shown that Atropol can inhibit the decomposition of glycogen in the worm body and has a significant and lasting inhibitory effect on both the anaerobic and aerobic metabolism of the worm body cells.

Agrimonia phenol has the effect of promoting the migration of schistosomiasis in animals to the liver and killing adult schistosomiasis. However, it is not very effective when used alone. When used together with a small dose of the synthetic drug nitrothiocarb, it can significantly improve the effect of treating animal schistosomiasis. The decoction of young stems and leaves of Agrimonia odorifera also has a good effect on vaginal Trichomonas.

4. Effects on the cardiovascular system The extract and agrimony extract have a cardiotonic effect on isolated frog hearts; they can increase the heart rate and contraction strength of frogs and toads. The alcohol extract of the water extract has an inhibitory effect on isolated frog hearts. The ethanol extract of agrimony can increase blood pressure when injected intravenously into anesthetized rabbits and dogs. The alcohol extract of its water extract can reduce the blood pressure of rabbits; when perfused into the hind limb blood vessels of rabbits and frogs, low concentrations cause blood vessels to contract, while high concentrations cause blood vessels to dilate. When the extract and water extract of agrimony are perfused into the rabbit ear blood vessels, low concentrations have no effect, but high concentrations cause dilation reactions, and can counteract the vasoconstrictive effect of adrenaline.

5. Effect on smooth muscle The ethanol extract of the water extract has an excitatory effect on the isolated intestinal tube of rabbits and guinea pigs at low concentrations, but an inhibitory effect at high concentrations. Agrimonia lactone can reduce the contraction amplitude and tension of the isolated rabbit intestine, and then stop the intestinal movement in a relaxed state; it also has an inhibitory effect on the peristalsis of the rat's in situ small intestine. The extract has an adrenaline-like effect on the isolated rabbit and guinea pig uterus.

Although cranesbill has good hemostatic effects, some taboos should still be observed when using it. For example, if the body is not experiencing continuous bleeding, then cranesbill cannot be used for treatment. In addition, people with allergic constitution should not use it. If you feel any discomfort during use, stop using it immediately.