The efficacy of Chinese medicine Polygala tube

Polygala tube, which we often call Polygala, is mainly a kind of Chinese medicinal material in the shape of a tube. Polygala has many effects and functions. It is a kind of herb in people's eyes. It can be used to treat many diseases. If you choose to use this Polygala tube, it also has the effect and function of calming the nerves. When fresh Polygala is dried, it can become a Chinese medicinal material. The tube of Polygala is relatively thin, and some people call it Polygala stick. So what are the effects of this Chinese medicine Polygala tube?

Polygala tenuifolia has an expectorant effect, but due to different experimental methods, its expectorant effect varies greatly. Using the phenol red excretion method in mice, the expectorant effect of Polygala tenuifolia was stronger than that of Platycodon grandiflorum, while using the dog respiratory secretion fluid measurement method, its effect was not as good as that of Platycodon grandiflorum. Other scholars have reported that oral administration of 1g/kg Polygala tenuifolia decoction to anesthetized dogs had no expectorant effect. Studies have found that the chemical composition and pharmacological effects of the root bark and root heartwood of Polygala tenuifolia are not exactly the same. The saponin content of the root heartwood of Polygala tenuifolia is only 4% of that of the root bark. The minimum effective dose of the former for expectorant in mice is 1.25g/kg, while the latter has no expectorant effect even at 50g/kg. It is speculated that the expectorant effect of Polygala tenuifolia may be due to the stimulating effect of the saponins it contains on the gastric mucosa, which reflexively promotes the increase in bronchial secretions. The antitussive and expectorant effects of raw Polygala tenuifolia and its processed decoctions on mice were observed using ammonia-induced cough method and colorimetry. The results showed that raw Polygala, honey-processed Polygala, ginger-processed Polygala, and roasted (licorice-processed) Polygala had significant antitussive effects; the high-dose raw Polygala, low-dose honey Polygala, and high-dose roasted Polygala groups also had significant expectorant and antihypertensive effects.

Polygala decoction has a transient central hypotensive effect. Intravenous injection of 0.125g/kg of 100% Polygala decoction can reduce blood pressure in anesthetized dogs to 60-70% of the original level. Intravenous injection of 0.5g/kg in anesthetized rabbits can also reduce blood pressure to 40-50% of the original level. However, the effect is short-lived and can return to the original level within 1-2 minutes. No rapid tolerance phenomenon was observed after repeated administration.

In vivo and in vitro experiments show that Polygala tenuifolia has a strong uterine stimulating effect. The 100% injection solution prepared from the water decoction of Polygala tenuifolia after ethanol precipitation has a strong excitatory and contractile effect on the isolated non-pregnant uterus of rats and mice. Polygala fluid extract can cause strong contraction of the pregnant and non-pregnant uterus of guinea pigs, rabbits, cats and dogs in vitro and in situ, and increase muscle tension. 3-6mL of 6.6% Polygala decoction injected intravenously also has a significant stimulating effect on the uterus of pregnant dogs.

Diuretic effect

The suspension made by cold soaking and concentrating the root of Polygala tenuifolia in 50% methanol was orally administered at 200 mg/kg to rats with edema caused by ligation of both jugular veins. The diuretic effect was 8.01, 1.11 ml/l00kg body weight, and the inhibition rate of congestive edema was 100%. Polygala tenuifolia saponins have the effects of eliminating edema and promoting diuresis. If used in combination with phenylbutazone, its diuretic effect will be enhanced.

Through the above introduction, we know about the effects and functions of Polygala tenuifolia. If you don’t know much about it, then take a look at the article we introduced. I guarantee that everyone will be able to understand the effects and functions of Polygala tenuifolia after reading it, and will be able to make full use of it in life. When using Polygala tenuifolia to treat diseases, symptomatic treatment must also be used.