Related effects of Shichangpu

Acorus calamus is a relatively common Chinese medicinal material. This Chinese medicinal material can achieve a therapeutic effect, but most people do not understand the efficacy of this medicinal material and do not pay much attention to it. If it is taken by mistake, it will be very bad for your body, causing side effects and may also cause physical damage. Therefore, you must know the efficacy of Acorus calamus before taking this Chinese medicinal material, so that it can achieve the effect of treating the disease with the right medicine.

Acorus calamus has a sedative effect. Both decoction and volatile oil can reduce the spontaneous activity of mice.

It can eliminate the aggressive behavior of mice kept in single cages; it can also prolong the sleep time caused by sodium pentobarbital, and has a synergistic effect on subthreshold hypnotic doses of sodium pentobarbital. In addition, it can significantly prolong the anesthesia time of sodium pentobarbital. Studies have shown that asarone in volatile oil is an effective sedative ingredient, but it still has a sedative effect after removing the volatile oil, suggesting that there is more than one sedative ingredient.

Acorus tatarinowii decoction has a certain antagonistic effect on convulsions in mice induced by pentylenetetrazol. Compared with the control group, it can reduce autonomous activities, delay the onset of convulsions, and reduce the number of convulsive mice. 140 mg/kg of α-asarone in the volatile oil can completely counteract electric seizures and pentylenetetrazol seizures in mice, and can counteract seizures caused by intracerebroventricular administration of ACh in rabbits. The water decoction without the volatile oil is also effective.

Acorus calamus volatile oil has a strong cooling effect on mice.

Tablets made from the water extract of Acorus calamus rhizomes are clinically used to treat epilepsy and other nervous system diseases with good therapeutic effects. Its volatile oil has significant physiological activity on certain animal models of the nervous system.

Effects on the cardiovascular system

The volatile oil of Acorus tatarinowii (β-asarone) has the effect of dilating the coronary vessels of guinea pigs at a certain concentration. It is commonly used clinically to treat chest pain caused by phlegm and qi stagnation in patients with coronary heart disease, cor pulmonale, etc. Its mechanism may be related to its ability to increase coronary blood flow, and may also be related to its sedative, improvement of digestive function, antiasthmatic, and antitussive effects.

Effects on the digestive system

Taking Acorus calamus decoction internally can promote the secretion of digestive juice, stop abnormal gastrointestinal fermentation, and relieve intestinal smooth muscle spasm. Asarone contained in Acorus calamus can counteract the excitatory effect of isolated intestine caused by barium chloride.

Antifungal effect

Acorus calamus water extract (1:3) has varying degrees of inhibitory effects on skin fungi such as Trichophyton violaceum, Trichophyton concentricum, Trichophyton thunbergii, Microspore Trichophyton audouinensis, Microspore Trichophyton ferruginosa, Microspore Trichophyton woolly, Epidermophyton inguinale, Epidermophyton rubrum, Epidermophyton kaufmann-wolfii, and Nocardia asteroides in vitro.

Other effects

The α-asarone contained in Acorus calamus has an antiasthmatic effect, can counteract the bronchoconstriction caused by histamine, and has an antitussive effect. Clinically, it improves the lung ventilation function of patients with bronchial asthma.