What is saline solution

As we all know, the efficacy and function of saline solution are very good. It is not only suitable for mammals and humans, but also has significant effects on other amphibians. In addition to providing us with a large amount of electrolytes, normal saline can also maintain the tension of our body fluids very well. It can also be used to clean wounds, etc. So what exactly is saline?

In fact, normal saline has many and wide uses. It is not only suitable for dehydration or diseases caused by acidosis, but can also be used for patients with liver and kidney problems. It can help relieve the symptoms of the disease and avoid the rupture of human cells. So what exactly is saline?

What is saline solution

Physiological saline refers to a sodium chloride solution commonly used in physiological experiments or clinical practice, whose osmotic pressure is equal to that of animal or human plasma. Concentration: 0.67-0.70% for amphibians, 0.85-0.9% for mammals and humans. The concentration of sodium chloride injection that people usually use for intravenous drips is 0.9%, which can be used as normal saline. Its osmotic pressure is similar to that of human blood, and its sodium content is also similar to that of plasma, but its chloride content is significantly higher than that in plasma. Therefore, normal saline is only relatively physiological, and its purpose is to supply electrolytes and maintain the tension of body fluids. It can also be used externally, such as cleaning wounds or changing dressings.

nature

Normal saline is also called sterile saline. Normal saline is a 0.9% sodium chloride aqueous solution. Because its osmotic pressure value is roughly the same as that of normal human plasma and tissue fluid, it can be used for fluid replacement (without reducing or increasing the sodium ion concentration in the normal human body) and other medical purposes. It is also often used for in vitro culture of living tissues and cells. It is the concentration of the liquid environment in which human cells are located.

Sodium chloride: commonly known as salt, table salt (without iodine).

effect

It can prevent cell rupture, and its osmotic pressure is the same as that outside the cells, so it will not cause the cells to become dehydrated or absorb excessive water. Therefore, it is used in many medical operations where liquids are needed. It is the concentration of the liquid environment in which human cells live. In order to correct dehydration and acidosis, different liquids are often mixed in proportion and used clinically. Why can't a single saline solution or 5% or 10% GS solution be used to correct dehydration and acidosis? This is because severe diarrhea in infants and young children, in addition to the loss of sodium bicarbonate and resulting in metabolic acidosis, also causes malnutrition (the so-called "starvation") ketoacidosis and a large loss of electrolytes and water. Therefore, a mixed solution is needed that can replenish electrolytes, correct acidosis, overcome ketosis, and replenish water and calories. The use of normal saline or 5% to 10% glucose solution alone cannot meet the above pathophysiological requirements. If normal saline is used alone for infusion, when sodium chloride has been replenished but dehydration has not been replenished, continuing to use normal saline will cause salt diuresis, and in severe cases, salt poisoning may occur. When only 5% to 10% GS is used for infusion, it will cause an extracellular hypotonic state, thereby reducing the secretion of antidiuretic hormone, causing diuresis. In severe cases, water intoxication may occur, causing neurological symptoms. The clinical manifestation is that the more fluid is replaced, the more urine is produced. This is the reason. However, since adults have sound liver and kidney functions, dehydrated patients can use the mixed solution as well as alternating intravenous injection of normal saline and 5% or 10% GS solution, that is, transfuse a 500ml bottle of normal saline and then a 500ml bottle of GS solution. When correcting acidosis, add alkaline solution into the GS solution bottle and drip it.

Everyone already knows what normal saline is. Physiological saline is also called sterile saline by people in the medical field. In addition, the osmotic pressure of physiological saline is roughly the same as that of our blood and even tissue fluid. Therefore, it is very suitable for the purpose of fluid replenishment, and can also be used to clean wounds and make them heal quickly. In addition, it can also relieve acidosis, etc., and normal saline is always an excellent solution.