The role and efficacy of wood fragrance

Medicine is very common in life. When treating diseases, it is also necessary to choose the right medicine, so that it can be of great help to improve the disease. There are many medicines for treating diseases, so when choosing, it is also necessary to understand all aspects of the medicine. Muxiang is a good choice for treating diseases. It has a good effect on gastrointestinal problems. What are the effects and functions of Muxiang?

Many people don’t know much about the effects and functions of costus root, and after choosing it, you also need to know what diseases it can treat. When choosing it, you can use it with confidence, especially when treating cardiovascular diseases, it cannot be used indiscriminately.

The role and efficacy of wood fragrance :

1. Effects on the gastrointestinal tract:

The extract of wood perfume, volatile oil and total bioalkali first had a mild excitatory effect on the isolated small intestine of rats, and then the tension and rhythmicity decreased significantly. The extract of costusroot can significantly enhance the amplitude of intestinal peristalsis and intestinal muscle tension of isolated rabbit intestines; it has an antagonistic effect on intestinal muscle spasm caused by Ach, histamine and BaCl2. Large doses of decoction, volatile oil, volatile oil without lactone, total lactone, and various lactone parts such as costus lactone and dihydrocostus lactone all have an inhibitory effect on the motility of isolated rabbit small intestine. Total bioalkali can counteract the spasmodic effect of Ach and histamine on the isolated guinea pig ileum. Delactone volatile oil, dihydrocostus lactone and total lactones can significantly inhibit the movement of large and small intestines in the body, reduce their tension and rhythmic contraction, while other lactone parts have less effect. Aquilaria alkaloids have a significant inhibitory effect on the isolated small intestine of rabbits and cats. Intravenous injection can also significantly inhibit the movement of the small intestine of cats in vivo, causing the intestinal muscles to relax and the movement to stop, but it is easy to recover.

2. Effects on the cardiovascular system:

Low concentrations of volatile oils and the lactone fractions separated from the volatile oils have varying degrees of inhibitory effects on the isolated hearts of a variety of animals. Small doses of water extract and alcohol extract can excite the hearts of frogs and dogs, while large doses have an inhibitory effect. Intravenous injection of albendazole has an excitatory effect on the heart of cats in vivo. Delactone volatile oil, total lactones, and 12-methoxy-dihydrocostus lactone can increase the perfusion volume of isolated rabbit ears and rat hind limb blood vessels, and have a significant vasodilation effect. Small doses of total biotin can dilate isolated rabbit ear blood vessels, while large doses can cause contraction reactions. Intravenous injection of delactone volatile oil, total lactones, costus lactone, dihydrocostus lactone, dehydrocostus lactone and 12-methoxy-dihydrocostus lactone can moderately reduce the blood pressure of anesthetized dogs, and the antihypertensive effect is relatively long-lasting.

3. Effects on the respiratory system:

Yunmu perfume extract, alcohol extract, volatile oil and total bioalkali can counteract the spasmodic effect of histamine and Ach on the bronchi in vitro. The total lactones, costus lactone, dihydrocostus lactone and other lactone components contained in the volatile oil as well as the lactone-free volatile oil can counteract the bronchoconstriction caused by histamine, Ach and BaCl2, among which dihydrocostus lactone is more effective. Intraperitoneal injection of total lactones of Costusroot, Costusroot lactone, dihydrocostusroot lactone or de-lactone volatile oil has a protective effect on guinea pigs that inhale lethal doses of histamine or Ach aerosol, can prolong the incubation period of asthma and reduce the mortality rate. Intravenous injection of albendazole can produce a bronchodilatory response in anesthetized cats.

Intravenous injection of water extract, alcohol extract, volatile oil, volatile oil without lactone and total bioalkali had a certain inhibitory effect on the respiration of anesthetized dogs, slowing down the frequency and reducing the amplitude, among which volatile oil had the strongest effect.

4. Anti-pathogenic microorganisms:

Volatile oils can inhibit the growth of streptococci, Staphylococci aureus and Staphylococci albus, and have weak effects on Escherichia coli and diphtheria. Yunmuxiang decoction has inhibitory effects on 10 fungi including Trichoderma and its Mongolian variant, and has a slight inhibitory effect on Salmonella paratyphi. Yunmuxiang also has an inhibitory effect on bovine tuberculosis and human tuberculosis.

5. Other functions:

Oral administration of the ethanol extract of Aucklandia lappa can lower the blood sugar level in rats. Costusroot lactone has cytotoxic effects on human nasopharyngeal carcinoma cells.

6. Toxicity:

LD50 of intraperitoneal injection in rats: total lactones are 300 mg/kg, and dihydrocostus lactone is 200 mg/kg. The MTD of total bioalkali after intravenous injection is 100 mg/kg for mice and 90 mg/kg for rats.

Through the above introduction, we have a good understanding of the role and efficacy of costus root, so choosing it to treat one's own diseases is also very helpful. Moreover, using it to treat one's own diseases will not harm any aspects of the body. It can treat the gastrointestinal tract, respiratory tract, cardiovascular and cerebrovascular systems.