Effects and functions of plant gold

Polygonatum sibiricum is an uncommon plant, but it has certain medicinal and health values. For this reason, Polygonatum sibiricum is still very popular in today's market. In addition, in clinical medicine, Polygonatum sibiricum is often used to make various medicines to resist and treat various types of diseases and restore people to health! Below, I will introduce to you in detail the functions and effects of Polygonatum!

1. Anti-pathogenic microorganisms

In vitro tests show that the water extract of Polygonatum sibiricum (1:320) has inhibitory effects on Salmonella typhi, Staphylococcus aureus, and acid-fast bacilli. 2% Polygonatum sibiricum has varying degrees of inhibitory effects on common pathogenic fungi in Sabouraud's medium.

2. Impact on blood sugar

When rabbits were gavaged with Polygonatum sibiricum extract, their blood sugar levels gradually increased and then decreased. Polygonatum sibiricum extract has a significant inhibitory effect on hyperglycemia caused by adrenaline.

3. Anti-fatigue effect

Intraperitoneal injection of 0.3 ml of 17.67% Polygonatum sibiricum decoction per mouse can prolong the swimming time of mice.

4. Antioxidant Effect

Feeding 20% ​​concentration of Polygonatum sibiricum decoction, 13 ml per mouse, for 27 consecutive days increased the activity of superoxide dismutase (SOD) in the mouse liver and reduced the content of myocardial lipofuscin.

5. Anti-aging effect

A 20% concentration of Polygonatum sibiricum decoction, soaked in mulberry leaves and fed to silkworms, has the effect of prolonging the larval stage of silkworms.

6. Hemostatic effect

40 mg/mouse of methanol extract of Polygonatum sibiricum, 20 mg/mouse of n-butanol fraction and 20 mg/mouse of aqueous fraction were injected intraperitoneally. The tail of mice was frozen with dry ice-methanol for 1 minute. The tail cutting experiment showed that it had a hemostatic effect and reduced the amount of bleeding in mice.

7. Effects on cardiovascular system

Intravenous injection of 0.16-0.26g/kg of Polygonatum sibiricum water extract significantly increased the coronary flow of anesthetized dogs; intravenous injection of 1.5g/kg had an antagonistic effect on myocardial ischemia in rabbits caused by vasopressin, antagonized the increase in T waves caused by vasopressin, and promoted the early recovery of T wave abnormalities; intraperitoneal injection of 12g/kg can enhance the tolerance of mice to hypoxia.

8. Antiviral effect

Polygonatum sibiricum polysaccharide 0.2% eye drops, 6 times/day, or taking Polygonatum sibiricum polysaccharide 10 mg/kg, 2 times/day, both have a therapeutic effect on experimental herpes simplex virus keratitis in rabbits.

9. Other functions

Oral administration of 6g/kg of Polygonatum sibiricum decoction for 10 consecutive days can increase the Na+, K+-ATPase activity of mouse erythrocyte membrane. Intraperitoneal injection of 0.3 ml of 40% Polygonatum sibiricum alcohol extract can increase the incorporation rate of 3H~TdR into the DNA of mouse myocardial, liver and spleen tissue cells. Oral administration of 0.5 g of Polygonatum sibiricum decoction to mice decreased the levels of plasma cAMP and cGMP, with cGMP decreasing more, so the cAMP/cGMP ratio was greater than that of the control group. The cAMP and cGMP levels in spleen tissue increased, but the cAMP/cGMP ratio did not change significantly.