What are the effects of traditional Chinese medicine Polygonum multiflorum

Polygonum multiflorum, also known as purple vine, is a well-known Chinese herbal medicine, but we don’t often come into contact with this kind of medicinal material in our daily life. Therefore, if you are not a professional, you will not know much about the effects of this medicine, let alone what diseases this medicine can be used to treat. Today we will learn about the effects of the Chinese medicine Polygonum multiflorum.

1. Promote hematopoietic function

Subcutaneous injection of 0.2 g of Shouwu liquid twice a day for 3 consecutive days in mice can significantly increase the yield of granulocyte progenitor cells compared with the saline control group. Intraperitoneal injection of 50 mg/kg of Polygonum multiflorum extract into mice for 3 consecutive days can significantly increase the number of bone marrow hematopoietic stem cells, significantly improve the production rate of mouse granulocyte-monocyte progenitor cells, and significantly increase the value of bone marrow erythroid progenitor cells.

2. Enhance immune function

Polygonum multiflorum has a significant antagonistic effect on the inhibitory changes in the spleen and thymus of aged mice caused by prednisolone and cyclophosphamide, and significantly increases the phagocytic rate and phagocytic index of splenic macrophages. Feeding Polygonum multiflorum ethanol extract can significantly improve the damage and repair ability of DNA in peripheral lymphocytes of elderly rats. Gavage of 6 g/kg of processed Polygonum multiflorum to mice for 7 consecutive days can significantly improve the phagocytic ability of peritoneal macrophages and have a significant antagonistic effect on the decrease in phagocytic index caused by prednisolone. The ethanol extract of Polygonum multiflorum decoction has an enhancing effect on the immune function of both T lymphocytes and B lymphocytes in mice, with the former having a more significant effect. Intraperitoneal injection of 25-100 mg/kg of Polygonum multiflorum extract for 3 consecutive days can significantly increase the ConA-induced thymus and spleen T lymphocyte proliferation response in normal mice; subcutaneous injection of 5-100 g/kg for 3 consecutive days can significantly increase the number of antibody-forming cells in the spleen of normal mice, with the most significant effect in the 50 g/kg group.

3. Lowering blood lipids and preventing atherosclerosis

Giving 4g/kg Polygonum multiflorum to rats with hyperlipidemia daily for 10 consecutive days can significantly reduce the levels of serum total cholesterol (TC) and serum triglyceride (TG) in rats. For quails with hyperlipidemia, continuous gavage of Polygonum multiflorum for 4 weeks can significantly reduce serum TC content and increase the HDL/TC ratio. Other experiments have shown that oral administration of Polygonum multiflorum for 7 days in rabbits with hyperlipidemia and atherosclerosis models can not only reduce TC content but also alleviate the formation of atherosclerotic plaques. Feeding mice with 32g/kg of Polygonum multiflorum water extract for one month can significantly increase HDL-C levels. When Polygonum multiflorum was added to feed and fed to rats for 90 days, HDL-C was significantly increased, while TG and TC showed no significant changes, and it had a significant inhibitory effect on β-lipoprotein. When the alcohol extract of Polygonum multiflorum was administered intragastrically to quails with rapid atherosclerosis for 6 consecutive weeks, the plasma HDL-C/TC ratio increased significantly, and the effect was more significant in the high-dose group. All drug-administered groups had the effect of delaying atherosclerosis. The active ingredients of Polygonum multiflorum that have lipid-lowering and anti-cholesterol effects include anthraquinones, diphenylene compounds and lecithin.

In the article, we have learned about the effects of the traditional Chinese medicine Polygonum multiflorum. In fact, Polygonum multiflorum can not only protect hair, but also enhance our own immunity. After all, the current environment is mostly polluted, so we need to drink some traditional Chinese medicine to nourish our body.