Is it effective to use Aconite and Pinellia together?

There are many kinds of Chinese medicine. Different herbs have different effects, and many herbs look very similar, so we should pay attention to distinguish them. Aconite can improve the myocardial contractility of the human body, dilate blood vessels, and effectively improve blood circulation. Pinellia is mainly used to treat phlegm, cough, asthma, and vomiting. So, is it effective to use Aconite and Pinellia together?

First, is there any effect when using aconite and pinellia together? Within the general clinical dosage range, the combination of pinellia with Chuanwu, Caowu or aconite will not increase toxicity or reduce efficacy, but it still needs to be cautious in clinical application to avoid adverse reactions. Pinellia ternata is neurotoxic. The precipitate of its water-soluble components after adding lead acetate contains substances that cause skeletal muscle spasms in frogs and mice and dilate the frog's pupils; the filtrate contains substances that cause central and curare-like skeletal muscle relaxation in frogs. Accidentally ingesting even a small amount of raw pinellia can cause poisoning, so raw pinellia is managed as a toxic Chinese medicine and needs to be processed before clinical use. In addition, Pinellia ternata has strong irritation to local mucous membranes, nephrotoxicity, embryotoxicity, and teratogenicity.

Second, among the 18 antidotes in traditional Chinese medicine, "Banluo Beishi and Gongwu", Pinellia is the antidote to Aconitum, but Aconitum and Aconitum are different parts of the same plant, Aconitum is the mother root and Aconitum is the daughter root. Therefore, according to the 18 antidotes, Pinellia and Aconitum cannot be used together, except for some experienced Chinese medicine doctors who are excellent in controlling the properties of drugs and making good combinations, and they use the opposing forces of Pinellia and Aconitum to achieve the effect of treating serious diseases. The combination of Aconite and Pinellia can improve the cardiac function of rats with ischemia-reperfusion, reduce the area of ​​myocardial infarction, and improve the ultrastructure of myocardial mitochondria, and has a protective effect on the specific pathological state of myocardial ischemia-reperfusion injury.

Is it effective to use aconite and pinellia together? In principle, aconite and pinellia cannot be used together. However, Zhong Sheng used aconite stem and rice soup together to take advantage of their opposite properties to stimulate the efficacy of the medicine. That is to say, sometimes the therapeutic effect of using Pinellia and Aconite together is better, but you still need to be cautious when using them.