Loxoprofen Sodium Tablets

Loxoprofen sodium tablets are a strong analgesic and anti-inflammatory drug with strong antipyretic, analgesic, anti-inflammatory and other effects. It has a good analgesic effect on rheumatoid arthritis, low back pain, frozen shoulder, etc. It also has a good analgesic effect on pain caused by surgery and trauma, and can be used for anti-inflammatory treatment after tooth extraction.

Loxoprofen sodium tablets can also be used to treat pain and inflammation caused by upper respiratory tract infections. You can take loxoprofen sodium tablets orally, but be careful not to take loxoprofen sodium tablets on an empty stomach. The maximum daily dose should not exceed 180 mg and can be taken as directed by a doctor.

According to literature reports: After oral administration, this product is quickly absorbed in the gastrointestinal tract and appears in the blood in the form of loxoprofen sodium and anti-OH metabolite (active metabolite), and is distributed in the liver, kidneys, and plasma at higher concentrations. After healthy adults take 60 mg orally, the peak time for the prototype drug is 30 minutes, and the active metabolite is about 50 minutes. The protein binding rate of the prototype is 97.0%, and the protein binding rate of the active metabolite is 92.8%. Most of them are then converted into glucuronic acid conjugates of the prototype or glucuronic acid conjugates of hydroxylated forms, which are mainly excreted rapidly in the urine, with about 50% excreted within 8 hours after oral administration. Take orally for 5 consecutive days without accumulation. The half-life of the prototype is 1.2h, and the half-life of the active metabolite is 1.3h.

When this product is used for chronic diseases (rheumatoid arthritis, osteoarthritis), the following precautions should be taken: When using the drug for a long time, clinical examinations (urine tests, blood tests, liver function tests, etc.) should be performed regularly. If abnormalities are found, the dosage should be reduced or use should be suspended and appropriate treatment should be given; treatment methods other than drug therapy should also be considered.

Long-term and excessive use of loxoprofen sodium tablets has obvious side effects and may cause the following adverse reactions: shock, hemolytic anemia, mucocutaneous mucositis syndrome, acute renal failure, interstitial pneumonia, etc. If these symptoms occur, you must go to the hospital for treatment immediately. In addition, patients with chronic major systemic diseases should not take loxoprofen sodium tablets.